سارافلوكساسين

سارافلوكساسين Sarafloxacin هو مضاد حيوي من زمرة الكينولون. تم سحبه من قبل الشركة المصنعة (مختبرات أبوت) في 30 أبريل 2001.

آلية العمل

تثبيط أنزيم الدنا جيراز اللازم لتضاعف الدنا الجرثومي.

لعلاج ومراقبة داء العصيات القولونية في الدواجن.

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

2,4-Diaminopyrimidine (Trimethoprim^# • Brodimoprim • Tetroxoprim • Iclaprim^†)

Short- acting	Sulfaisodimidine • Sulfamethizole • Sulfadimidine • Sulfapyridine • Sulfafurazole • Sulfanilamide (Prontosil) • Sulfathiazole • Sulfathiourea

Intermediate- acting	Sulfamethoxazole • Sulfadiazine^# • Sulfamoxole

Long- acting	Sulfadimethoxine • Sulfadoxine • Sulfalene • Sulfametomidine • Sulfametoxydiazine • Sulfamethoxypyridazine • Sulfaperin • Sulfamerazine • Sulfaphenazole • Sulfamazone

Other/ungrouped

Combinations

2nd g.	Ciprofloxacin^# • Enoxacin^‡ • Fleroxacin^‡ • Lomefloxacin • Nadifloxacin • Ofloxacin • Norfloxacin • Pefloxacin • Rufloxacin

3rd g.	Balofloxacin • Grepafloxacin^‡ • Levofloxacin • Pazufloxacin • Sparfloxacin^‡ • Temafloxacin^‡ • Tosufloxacin

4th g.	Besifloxacin • Clinafloxacin^† • Garenoxacin • Gemifloxacin • Moxifloxacin • Gatifloxacin^‡ • Sitafloxacin • Trovafloxacin^‡/Alatrofloxacin^‡ • Prulifloxacin

Vet.	Danofloxacin • Difloxacin • Enrofloxacin • Ibafloxacin • Marbofloxacin • Orbifloxacin • Pradofloxacin • Sarafloxacin

Related (DG)	Aminocoumarins: Novobiocin

Nitro- imidazole derivatives	Metronidazole^# • Tinidazole • Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# • Furazolidone^‡ • Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# • Rifabutin • Rifapentine • Rifaximin

drug (J1p, w, n, m, vacc)