الفرق بين المراجعتين لصفحة: «مانيتول»
اذهب إلى التنقل
اذهب إلى البحث
كنان الطرح (نقاش | مساهمات) (أنشأ الصفحة ب'thumb|250px '''مانيتول (Mannitol)''' مدر بول، خافض توتر شرياني. ==الاسم العلمي== (2R,3R,4R,5R)-Hex...') |
كنان الطرح (نقاش | مساهمات) لا ملخص تعديل |
||
| سطر 1: | سطر 1: | ||
{{Use dmy dates|date=November 2010}} | |||
''' | {{Drugbox | ||
| English = Mannitol | |||
| Watchedfields = changed | |||
| verifiedrevid = 456482551 | |||
| IUPAC_name = (2''R'',3''R'',4''R'',5''R'')-Hexan-1,2,3,4,5,6-hexol | |||
| image = Mannitol structure.png | |||
| image2 = D-Mannitol 3d space fill.png | |||
| drug_name = <small>D</small>-Mannitol | |||
== | <!--Clinical data--> | ||
| tradename = Osmitrol | |||
| Drugs.com = {{drugs.com|monograph|mannitol}} | |||
| pregnancy_category = C: ([[United States|USA]]) | |||
| routes_of_administration = [[Intravenous]]<br>[[Mouth|Oral]] | |||
== | <!--Pharmacokinetic data--> | ||
| bioavailability = ~7% | |||
| metabolism = [[Liver|Hepatic]], negligible. | |||
| elimination_half-life = 100 minutes | |||
| excretion = [[Kidney|Renal]]: 90% | |||
<!--Identifiers--> | |||
| CASNo_Ref = {{cascite}} | |||
| CAS_number_Ref = {{cascite|correct|??}} | |||
| CAS_number = 69–65–8 | |||
| ATC_prefix = A06 | |||
| ATC_suffix = AD16 | |||
| ATC_supplemental = {{ATC|B05|BC01}} {{ATC|B05|CX04}} {{ATC|R05|CB16}} | |||
| ChEBI_Ref = {{ebicite|correct|EBI}} | |||
| ChEBI = 16899 | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = FBPFZTCFMRRESA-KVTDHHQDSA-N | |||
| PubChem = 6251 | |||
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | |||
| DrugBank = DB00742 | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 6015 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = 3OWL53L36A | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D00062 | |||
| ChEMBL_Ref = {{ebicite|correct|EBI}} | |||
| ChEMBL = 689 | |||
<!--Chemical data--> | |||
== | | C=6 | H=14 | O=6 | ||
| molecular_weight = 182.172 | |||
| smiles = O[C@H]([C@H](O)CO)[C@H](O)[C@H](O)CO | |||
| InChI = 1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1 | |||
| InChIKey = FBPFZTCFMRRESA-KVTDHHQDBH | |||
}} | |||
'''مانيتول (Mannitol)''' [[مدر بول]]، [[خافض توتر شرياني]]. | |||
==أقرأ أيضاً== | ==أقرأ أيضاً== | ||
المراجعة الحالية بتاريخ 21:10، 1 مايو 2013
| |
|---|---|
| |
| Systematic (IUPAC) name | |
| (2R,3R,4R,5R)-Hexan-1,2,3,4,5,6-hexol | |
| Clinical data | |
| Trade names | Osmitrol |
| AHFS/Drugs.com | monograph |
| Pregnancy cat. | C: (USA) |
| Legal status | ? |
| Routes | Intravenous Oral |
| Pharmacokinetic data | |
| Bioavailability | ~7% |
| Metabolism | Hepatic, negligible. |
| Half-life | 100 minutes |
| Excretion | Renal: 90% |
| Identifiers | |
| CAS number | 69–65–8 
|
| ATC code | A06AD16 B05BC01 B05CX04 R05CB16 |
| PubChem | CID 6251 |
| DrugBank | DB00742 |
| ChemSpider | 6015
|
| UNII | 3OWL53L36A
|
| KEGG | D00062
|
| ChEBI | CHEBI:16899
|
| ChEMBL | CHEMBL689
|
| Chemical data | |
| Formula | C6H14O6 |
| Mol. mass | 182.172 |
| |
| |
 (what is this?) (verify) | |
مانيتول (Mannitol) مدر بول، خافض توتر شرياني.