الفرق بين المراجعتين لصفحة: «قالب:مضادات الفيروسات القهقرية المستخدمة ضد فيروس الإيدز»

من موسوعة العلوم العربية
اذهب إلى التنقل اذهب إلى البحث
(وضع رابط للقالب الإنكليزي من ويكيبيديا ضمن شريط العنوان للقالب)
لا ملخص تعديل
 
(3 مراجعات متوسطة بواسطة مستخدمين اثنين آخرين غير معروضة)
سطر 1: سطر 1:
{{Navbox
{{Navbox
| name  = Antiretroviral drug
| name  = Antiretroviral drug
| title = [[Antiviral drug]]s: [[antiretroviral drug]]s used against [[HIV]] (primarily [[ATC code J05|J05]] [http://en.wikipedia.org/wiki/Template:Antiretroviral_drug القالب الإنكليزي])
| title = [[Antiviral drug]]s: [[antiretroviral drug]]s used against [[HIV]] (primarily [[ATC code J05|J05]])
|listclass = hlist
|state = {{{state<includeonly>|autocollapse</includeonly>}}}
|state = {{{state<includeonly>|autocollapse</includeonly>}}}
| groupstyle = background:PowderBlue;
| groupstyle = background:PowderBlue;
| belowstyle = background:#EE82EE;


| group1 = [[Entry inhibitor|Entry/fusion inhibitors]] </br> ''([[Discovery and development of CCR5 receptor antagonists|Discovery & development]])''
| group1 = [[Entry inhibitor|Entry/fusion inhibitors]] </br> ''([[Discovery and development of CCR5 receptor antagonists|Discovery & development]])''
| list1  = ''[[gp41]]'' ([[Enfuvirtide]]){{·}}  ''[[CCR5]]'' ([[Maraviroc]], [[Vicriviroc]]<sup>†</sup>, [[PRO 140]]<sup>†</sup>){{·}} ''[[CD4]]'' ([[Ibalizumab]]<sup>†</sup>)
| list1  =
* ''[[gp41]]'' ([[Enfuvirtide]])
* ''[[CCR5]]'' ([[Maraviroc]]
* [[Vicriviroc]]<sup>†</sup>, [[Cenicriviroc]]<sup>†</sup>, [[PRO 140]]<sup>†</sup>)
* ''[[CD4]]'' ([[Ibalizumab]]<sup>†</sup>)


| group2 = [[Reverse transcriptase inhibitor|Reverse transcriptase<br/> inhibitors]] (RTIs)
| group2 = [[Reverse-transcriptase inhibitor|Reverse-transcriptase<br/> inhibitors]] (RTIs)
| list2  =  
| list2  =  
{{Navbox subgroup
{{Navbox subgroup
| groupstyle = background:PowderBlue;
| groupstyle = background:PowderBlue;


| group1 = [[Reverse transcriptase inhibitor|Nucleoside &<br/> Nucleotide (NRTI)]]
| group1 = [[Reverse transcriptase inhibitor|Nucleoside &<br/> nucleotide (NRTI)]]
| list1  = ''[[Nucleoside analogue]]s/[[Reverse_transcriptase_inhibitor#Nucleoside_analog_reverse_transcriptase_inhibitors_.28NARTIs_or_NRTIs.29|NARTIs]]:''  [[Abacavir|Abacavir (ABC)]]°<sup>#</sup>{{·}}  [[Emtricitabine|Emtricitabine (FTC)]]°<sup>#</sup>{{·}} [[Lamivudine|Lamivudine (3TC)]]°<sup>#</sup>{{·}} [[Didanosine|Didanosine (ddI)]]<sup>#</sup>{{·}} [[Zidovudine|Zidovudine (AZT)]]<sup>#</sup>{{·}} [[Apricitabine]]<sup>†</sup>{{·}} [[Stampidine]]<sup>†</sup>{{·}} [[Elvucitabine]]<sup>†</sup>{{·}} [[Racivir]]<sup>†</sup>{{·}} [[Amdoxovir]]<sup>†</sup>{{·}}  [[Stavudine|Stavudine (d4T)]]<sup>#</sup>{{·}} [[Zalcitabine|Zalcitabine (ddC)]]<sup>◊</sup><BR>
| list1  =
* ''[[Nucleoside analogue]]s/[[Reverse transcriptase inhibitor#Nucleoside analog reverse transcriptase inhibitors .28NARTIs or NRTIs.29|NARTIs]]:''  [[Abacavir|Abacavir (ABC)]]°<sup>#</sup>
* [[Emtricitabine|Emtricitabine (FTC)]]°<sup>#</sup>
* [[Lamivudine|Lamivudine (3TC)]]°<sup>#</sup>
* [[Didanosine|Didanosine (ddI)]]<sup>#</sup>
* [[Zidovudine|Zidovudine (AZT)]]<sup>#</sup>
* [[Apricitabine]]<sup>†</sup>
* [[Stampidine]]<sup>†</sup>
* [[Elvucitabine]]<sup>†</sup>
* [[Racivir]]<sup>†</sup>
* [[Amdoxovir]]<sup>†</sup>
* [[Stavudine|Stavudine (d4T)]]<sup>#</sup>
* [[Zalcitabine|Zalcitabine (ddC)]]<sup>◊</sup>
* [[Festinavir]]<sup>†</sup>&nbsp;


''[[Nucleotide analogue]]s/[[Reverse_transcriptase_inhibitor#Nucleotide_analog_reverse_transcriptase_inhibitors_.28NtARTIs_or_NtRTIs.29|NtRTI]]s:''  [[Tenofovir]]°<sup>#</sup>
*''[[Nucleotide analogue]]s/[[Reverse transcriptase inhibitor#Nucleotide analog reverse transcriptase inhibitors .28NtARTIs or NtRTIs.29|NtRTI]]s:''  [[Tenofovir disoproxil fumarate|Tenofovir disoproxil fumarate (TDF)]]°<sup>#</sup>
* [[Tenofovir alafenamide fumarate|Tenofovir alafenamide fumarate (TAF)]]<sup>†</sup>


| group2 = [[Reverse_transcriptase_inhibitor#Non-nucleoside_reverse_transcriptase_inhibitors_.28NNRTIs.29|Non-Nucleoside (NNRTI)]]<br/>''([[Discovery and development of non-nucleoside reverse transcriptase inhibitors|Discovery & development]])''
| group2 = [[Reverse transcriptase inhibitor#Non-nucleoside reverse transcriptase inhibitors (NNRTIs)|Non-nucleoside (NNRTI)]]<br/>''([[Discovery and development of non-nucleoside reverse transcriptase inhibitors|Discovery & development]])''
| list2  = ''(1st gen) [[Efavirenz]]°<sup>#</sup>{{·}} [[Nevirapine]]<sup>#</sup> {{·}} [[Loviride]]<sup>◊</sup>{{·}} [[Delavirdine]]<sup>◊</sup>{{·}}</br> ''(2nd gen)'' ''[[diarylpyrimidines]]'' ([[Etravirine]], [[Rilpivirine]]<sup>†</sup>) {{·}} [[Discovery_and_Development_of_Non-Nucleoside_Reverse_Transcriptase_Inhibitors#Lersivirine_.28UK-453061.29|Lersivirine]]<sup>†</sup>
| list2  =
* ''(1<sup>st</sup> generation)'' [[Efavirenz|Efavirenz (EFV)]]°<sup>#</sup>
* [[Nevirapine|Nevirapine (NVP)]]<sup>#</sup>  
* [[Loviride]]<sup>◊</sup>
* [[Delavirdine|Delavirdine (DLV)]]<sup>◊</sup>
* </br> ''(2<sup>nd</sup> generation)'' ''[[diarylpyrimidines]]'' ([[Etravirine]]
* [[Rilpivirine]])  
* [[Lersivirine]]<sup>†</sup>




}}
}}
| group3 = [[Integrase inhibitor]]s
| group3 = [[Integrase inhibitor]]s
| list3  = [[Raltegravir]]{{·}} [[Elvitegravir]]<sup>†</sup>{{·}} [[Globoidnan A]] (experimental) {{·}} [[MK-2048]]<sup>†</sup> {{·}} [[GSK-572]]<sup>†</sup>
| list3  =
* [[Raltegravir]]°
* [[Elvitegravir]]
* [[Dolutegravir]]<sup>†</sup>
* [[Globoidnan A]] (experimental)  
* [[MK-2048]]<sup>†</sup>  
* [[BI 224436]]<sup>†</sup>
* [[GSK744]]<sup>†</sup> &nbsp;
| group4 = [[Maturation inhibitor]]s
| group4 = [[Maturation inhibitor]]s
| list4 = [[Bevirimat]]<sup>†</sup>{{·}} [[Vivecon]]<sup>†</sup>  
| list4 =
* [[Bevirimat]]<sup>†</sup>


| group5 = [[Protease inhibitor (pharmacology)|Protease Inhibitors (PI)]]</br>''([[Discovery and development of HIV protease inhibitors|Discovery and development]])''
| group5 = [[Protease inhibitor (pharmacology)|Protease Inhibitors (PI)]]</br>''([[Discovery and development of HIV protease inhibitors|Discovery and development]])''
| list5  =  [[Atazanavir]]°{{·}} [[Fosamprenavir]]°{{·}} [[Lopinavir]]°<sup>#</sup>{{·}} [[Darunavir]]{{·}} [[Nelfinavir]]<sup>#</sup>{{·}} [[Ritonavir]]<sup>#</sup>{{·}} [[Saquinavir]]<sup>#</sup>{{·}} [[Tipranavir]]{{·}} [[Amprenavir]]<sup>◊</sup>{{·}} [[Indinavir]]<sup>◊</sup><sup>#</sup>
| list5  =   


{{Navbox subgroup
| groupstyle = background:PowderBlue;
| group1 = 1<sup>st</sup> generation
| list1  =
* [[Fosamprenavir]]°
* [[Lopinavir]]°<sup>#</sup>
* [[Nelfinavir]]<sup>#</sup>
* [[Ritonavir]]<sup>#</sup>
* [[Saquinavir]]<sup>#</sup>
* [[Amprenavir]]<sup>◊</sup>
* [[Indinavir]]<sup>◊</sup><sup>#</sup>
| group2 =2<sup>nd</sup> generation
| list2  =
* [[Atazanavir]]°
* [[Darunavir]]°
* [[Tipranavir]]&nbsp; 
}}


| group6 = [[Fixed dose combination (antiretroviral)|Combined formulations]]
| group6 = [[Fixed-dose combination (antiretroviral)|Combined formulations]]
| list6 = [[Combivir]]{{·}} [[Atripla]]{{·}} [[Trizivir]]{{·}} [[Truvada]]{{·}} [[Kaletra]]{{·}} [[Epzicom]]  
| list6 =
* [[Lamivudine/zidovudine]]
* [[Emtricitabine/tenofovir/efavirenz]]
* [[Abacavir/lamivudine/zidovudine]]
* [[Tenofovir/emtricitabine]]
* [[Lopinavir/ritonavir]]
* [[Abacavir/lamivudine]]
* [[Emtricitabine/rilpivirine/tenofovir]]  
* [[Elvitegravir/cobicistat/emtricitabine/tenofovir]]


| group7 = Experimental agents
| group7 = Experimental agents
سطر 41: سطر 103:
| groupstyle = background:PowderBlue;
| groupstyle = background:PowderBlue;


| group1 = [[Antiviral_drug#Uncoating_inhibitor|Uncoating inhibitor]]s
| group1 = [[Antiviral drug#Uncoating inhibitor|Uncoating inhibitor]]s
| list1  = [[TRIM5alpha]] (gene)
| list1  =
* [[TRIM5alpha]] (gene)


| group2 = [[Transcription (genetics)|Transcription inhibitor]]s
| group2 = [[Transcription (genetics)|Transcription inhibitor]]s
| list2  = [[Tat_(HIV)#Clinical_significance|Tat antagonist]]s
| list2  =
* [[Tat (HIV)#Clinical significance|Tat antagonist]]s


| group3 = [[Antiviral_drug#Translation_.2F_ribozymes|Translation inhibitor]]s
| group3 = [[Antiviral drug#Translation .2F ribozymes|Translation inhibitor]]s
| list3  = [[Trichosanthin]]
| list3  =
* [[Trichosanthin]]


| group4 = Other
| group4 = Other
| list4  = [[Abzyme]]{{·}} [[Calanolide A]]{{·}} [[Ceragenin]]{{·}} [[Cyanovirin-N]]{{·}} [[Diarylpyrimidines]]{{·}} [[Epigallocatechin gallate|Epigallocatechin gallate (EGCG)]]{{·}} [[Foscarnet]]{{·}} [[Griffithsin]]{{·}} [[Hydroxycarbamide]]{{·}} [[Miltefosine]]{{·}} [[Portmanteau inhibitor]]s{{·}} [[Seliciclib]]<sup>†</sup>{{·}} [[Synergistic enhancer (antiretroviral)|Synergistic enhancer]]s{{·}} [[Tre recombinase]]{{·}} [[Zinc finger protein transcription factor]]{{·}} [[Error catastrophe#KP-1461|KP-1461]]<sup>†</sup>
| list4  =
 
* [[Abzyme]]
* [[Calanolide A]]
* [[Ceragenin]]
* [[Cyanovirin-N]]
* [[Diarylpyrimidines]]
* [[Epigallocatechin gallate|Epigallocatechin gallate (EGCG)]]
* [[Foscarnet]]
* [[Griffithsin]]
* [[Hydroxycarbamide]]
* [[Miltefosine]]
* [[Portmanteau inhibitor]]s
* [[Seliciclib]]<sup>†</sup>
* [[Synergistic enhancer (antiretroviral)|Synergistic enhancer]]s
* [[Tre recombinase]]
* [[Zinc finger protein transcription factor]]
* [[Error catastrophe#KP-1461|KP-1461]]<sup>†</sup>
* [[Cobicistat]]<sup>†</sup>
| group5 = Failed agents
| group5 = Failed agents
| list5  = [[Dexelvucitabine]]{{·}} [[Capravirine]]{{·}} [[Emivirine]]{{·}} [[Lodenosine]]{{·}} [[Atevirdine]]{{·}} [[Brecanavir]]{{·}} [[Aplaviroc]]
| list5  =
* [[Dexelvucitabine]]
* [[Capravirine]]
* [[Emivirine]]
* [[Lodenosine]]
* [[Atevirdine]]
* [[Brecanavir]]
* [[Aplaviroc]]
}}  
}}  


|belowstyle = background: transparent; padding: 0px;
|below = {{PharmNavFootnote}} °[[United States Department of Health and Human Services|DHHS]] preferred [[first-line treatment|first-line agent]]. <sup>◊</sup>Formerly or rarely used agent.<BR>{{Virus navs}}
|below = {{PharmNavFootnote}} °[[United States Department of Health and Human Services|DHHS]] preferred [[first-line treatment|first-line agent]]. <sup>◊</sup>Formerly or rarely used agent.<BR>{{Virus navs}}
}}<noinclude>
}}<noinclude>
[[تصنيف:جداول تصفح الأدوية|{{PAGENAME}}]]
[[تصنيف:جداول تصفح الأدوية]]
[[Category:Antiretroviral drugs|{{PAGENAME}}]]  
</noinclude>
</noinclude>

المراجعة الحالية بتاريخ 14:00، 9 أغسطس 2013