الفرق بين المراجعتين لصفحة: «قالب:مضادات الفيروسات القهقرية المستخدمة ضد فيروس الإيدز»

من موسوعة العلوم العربية
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(أنشأ الصفحة ب'{{Navbox | name = Antiretroviral drug | title = Antiviral drugs: antiretroviral drugs used against HIV (primarily J05) |state = {{{state<inclu...')
 
لا ملخص تعديل
 
(4 مراجعات متوسطة بواسطة 3 مستخدمين غير معروضة)
سطر 2: سطر 2:
| name  = Antiretroviral drug
| name  = Antiretroviral drug
| title = [[Antiviral drug]]s: [[antiretroviral drug]]s used against [[HIV]] (primarily [[ATC code J05|J05]])
| title = [[Antiviral drug]]s: [[antiretroviral drug]]s used against [[HIV]] (primarily [[ATC code J05|J05]])
|listclass = hlist
|state = {{{state<includeonly>|autocollapse</includeonly>}}}
|state = {{{state<includeonly>|autocollapse</includeonly>}}}
| groupstyle = background:PowderBlue;
| groupstyle = background:PowderBlue;
| belowstyle = background:#EE82EE;


| group1 = [[Entry inhibitor|Entry/fusion inhibitors]] </br> ''([[Discovery and development of CCR5 receptor antagonists|Discovery & development]])''
| group1 = [[Entry inhibitor|Entry/fusion inhibitors]] </br> ''([[Discovery and development of CCR5 receptor antagonists|Discovery & development]])''
| list1  = ''[[gp41]]'' ([[Enfuvirtide]]){{·}}  ''[[CCR5]]'' ([[Maraviroc]], [[Vicriviroc]]<sup>†</sup>, [[PRO 140]]<sup>†</sup>){{·}} ''[[CD4]]'' ([[Ibalizumab]]<sup>†</sup>)
| list1  =
* ''[[gp41]]'' ([[Enfuvirtide]])
* ''[[CCR5]]'' ([[Maraviroc]]
* [[Vicriviroc]]<sup>†</sup>, [[Cenicriviroc]]<sup>†</sup>, [[PRO 140]]<sup>†</sup>)
* ''[[CD4]]'' ([[Ibalizumab]]<sup>†</sup>)


| group2 = [[Reverse transcriptase inhibitor|Reverse transcriptase<br/> inhibitors]] (RTIs)
| group2 = [[Reverse-transcriptase inhibitor|Reverse-transcriptase<br/> inhibitors]] (RTIs)
| list2  =  
| list2  =  
{{Navbox subgroup
{{Navbox subgroup
| groupstyle = background:PowderBlue;
| groupstyle = background:PowderBlue;


| group1 = [[Reverse transcriptase inhibitor|Nucleoside &<br/> Nucleotide (NRTI)]]
| group1 = [[Reverse transcriptase inhibitor|Nucleoside &<br/> nucleotide (NRTI)]]
| list1  = ''[[Nucleoside analogue]]s/[[Reverse_transcriptase_inhibitor#Nucleoside_analog_reverse_transcriptase_inhibitors_.28NARTIs_or_NRTIs.29|NARTIs]]:''  [[Abacavir|Abacavir (ABC)]]°<sup>#</sup>{{·}}  [[Emtricitabine|Emtricitabine (FTC)]]°<sup>#</sup>{{·}} [[Lamivudine|Lamivudine (3TC)]]°<sup>#</sup>{{·}} [[Didanosine|Didanosine (ddI)]]<sup>#</sup>{{·}} [[Zidovudine|Zidovudine (AZT)]]<sup>#</sup>{{·}} [[Apricitabine]]<sup>†</sup>{{·}} [[Stampidine]]<sup>†</sup>{{·}} [[Elvucitabine]]<sup>†</sup>{{·}} [[Racivir]]<sup>†</sup>{{·}} [[Amdoxovir]]<sup>†</sup>{{·}}  [[Stavudine|Stavudine (d4T)]]<sup>#</sup>{{·}} [[Zalcitabine|Zalcitabine (ddC)]]<sup>◊</sup><BR>
| list1  =
* ''[[Nucleoside analogue]]s/[[Reverse transcriptase inhibitor#Nucleoside analog reverse transcriptase inhibitors .28NARTIs or NRTIs.29|NARTIs]]:''  [[Abacavir|Abacavir (ABC)]]°<sup>#</sup>
* [[Emtricitabine|Emtricitabine (FTC)]]°<sup>#</sup>
* [[Lamivudine|Lamivudine (3TC)]]°<sup>#</sup>
* [[Didanosine|Didanosine (ddI)]]<sup>#</sup>
* [[Zidovudine|Zidovudine (AZT)]]<sup>#</sup>
* [[Apricitabine]]<sup>†</sup>
* [[Stampidine]]<sup>†</sup>
* [[Elvucitabine]]<sup>†</sup>
* [[Racivir]]<sup>†</sup>
* [[Amdoxovir]]<sup>†</sup>
* [[Stavudine|Stavudine (d4T)]]<sup>#</sup>
* [[Zalcitabine|Zalcitabine (ddC)]]<sup>◊</sup>
* [[Festinavir]]<sup>†</sup>&nbsp;


''[[Nucleotide analogue]]s/[[Reverse_transcriptase_inhibitor#Nucleotide_analog_reverse_transcriptase_inhibitors_.28NtARTIs_or_NtRTIs.29|NtRTI]]s:''  [[Tenofovir]]°<sup>#</sup>
*''[[Nucleotide analogue]]s/[[Reverse transcriptase inhibitor#Nucleotide analog reverse transcriptase inhibitors .28NtARTIs or NtRTIs.29|NtRTI]]s:''  [[Tenofovir disoproxil fumarate|Tenofovir disoproxil fumarate (TDF)]]°<sup>#</sup>
* [[Tenofovir alafenamide fumarate|Tenofovir alafenamide fumarate (TAF)]]<sup>†</sup>


| group2 = [[Reverse_transcriptase_inhibitor#Non-nucleoside_reverse_transcriptase_inhibitors_.28NNRTIs.29|Non-Nucleoside (NNRTI)]]<br/>''([[Discovery and development of non-nucleoside reverse transcriptase inhibitors|Discovery & development]])''
| group2 = [[Reverse transcriptase inhibitor#Non-nucleoside reverse transcriptase inhibitors (NNRTIs)|Non-nucleoside (NNRTI)]]<br/>''([[Discovery and development of non-nucleoside reverse transcriptase inhibitors|Discovery & development]])''
| list2  = ''(1st gen) [[Efavirenz]]°<sup>#</sup>{{·}} [[Nevirapine]]<sup>#</sup> {{·}} [[Loviride]]<sup>◊</sup>{{·}} [[Delavirdine]]<sup>◊</sup>{{·}}</br> ''(2nd gen)'' ''[[diarylpyrimidines]]'' ([[Etravirine]], [[Rilpivirine]]<sup>†</sup>) {{·}} [[Discovery_and_Development_of_Non-Nucleoside_Reverse_Transcriptase_Inhibitors#Lersivirine_.28UK-453061.29|Lersivirine]]<sup>†</sup>
| list2  =
* ''(1<sup>st</sup> generation)'' [[Efavirenz|Efavirenz (EFV)]]°<sup>#</sup>
* [[Nevirapine|Nevirapine (NVP)]]<sup>#</sup>  
* [[Loviride]]<sup>◊</sup>
* [[Delavirdine|Delavirdine (DLV)]]<sup>◊</sup>
* </br> ''(2<sup>nd</sup> generation)'' ''[[diarylpyrimidines]]'' ([[Etravirine]]
* [[Rilpivirine]])  
* [[Lersivirine]]<sup>†</sup>




}}
}}
| group3 = [[Integrase inhibitor]]s
| group3 = [[Integrase inhibitor]]s
| list3  = [[Raltegravir]]{{·}} [[Elvitegravir]]<sup>†</sup>{{·}} [[Globoidnan A]] (experimental) {{·}} [[MK-2048]]<sup>†</sup> {{·}} [[GSK-572]]<sup>†</sup>
| list3  =
* [[Raltegravir]]°
* [[Elvitegravir]]
* [[Dolutegravir]]<sup>†</sup>
* [[Globoidnan A]] (experimental)  
* [[MK-2048]]<sup>†</sup>  
* [[BI 224436]]<sup>†</sup>
* [[GSK744]]<sup>†</sup> &nbsp;
| group4 = [[Maturation inhibitor]]s
| group4 = [[Maturation inhibitor]]s
| list4 = [[Bevirimat]]<sup>†</sup>{{·}} [[Vivecon]]<sup>†</sup>  
| list4 =
* [[Bevirimat]]<sup>†</sup>


| group5 = [[Protease inhibitor (pharmacology)|Protease Inhibitors (PI)]]</br>''([[Discovery and development of HIV protease inhibitors|Discovery and development]])''
| group5 = [[Protease inhibitor (pharmacology)|Protease Inhibitors (PI)]]</br>''([[Discovery and development of HIV protease inhibitors|Discovery and development]])''
| list5  =  [[Atazanavir]]°{{·}} [[Fosamprenavir]]°{{·}} [[Lopinavir]]°<sup>#</sup>{{·}} [[Darunavir]]{{·}} [[Nelfinavir]]<sup>#</sup>{{·}} [[Ritonavir]]<sup>#</sup>{{·}} [[Saquinavir]]<sup>#</sup>{{·}} [[Tipranavir]]{{·}} [[Amprenavir]]<sup>◊</sup>{{·}} [[Indinavir]]<sup>◊</sup><sup>#</sup>
| list5  =   


{{Navbox subgroup
| groupstyle = background:PowderBlue;
| group1 = 1<sup>st</sup> generation
| list1  =
* [[Fosamprenavir]]°
* [[Lopinavir]]°<sup>#</sup>
* [[Nelfinavir]]<sup>#</sup>
* [[Ritonavir]]<sup>#</sup>
* [[Saquinavir]]<sup>#</sup>
* [[Amprenavir]]<sup>◊</sup>
* [[Indinavir]]<sup>◊</sup><sup>#</sup>
| group2 =2<sup>nd</sup> generation
| list2  =
* [[Atazanavir]]°
* [[Darunavir]]°
* [[Tipranavir]]&nbsp; 
}}


| group6 = [[Fixed dose combination (antiretroviral)|Combined formulations]]
| group6 = [[Fixed-dose combination (antiretroviral)|Combined formulations]]
| list6 = [[Combivir]]{{·}} [[Atripla]]{{·}} [[Trizivir]]{{·}} [[Truvada]]{{·}} [[Kaletra]]{{·}} [[Epzicom]]  
| list6 =
* [[Lamivudine/zidovudine]]
* [[Emtricitabine/tenofovir/efavirenz]]
* [[Abacavir/lamivudine/zidovudine]]
* [[Tenofovir/emtricitabine]]
* [[Lopinavir/ritonavir]]
* [[Abacavir/lamivudine]]
* [[Emtricitabine/rilpivirine/tenofovir]]  
* [[Elvitegravir/cobicistat/emtricitabine/tenofovir]]


| group7 = Experimental agents
| group7 = Experimental agents
سطر 41: سطر 103:
| groupstyle = background:PowderBlue;
| groupstyle = background:PowderBlue;


| group1 = [[Antiviral_drug#Uncoating_inhibitor|Uncoating inhibitor]]s
| group1 = [[Antiviral drug#Uncoating inhibitor|Uncoating inhibitor]]s
| list1  = [[TRIM5alpha]] (gene)
| list1  =
* [[TRIM5alpha]] (gene)


| group2 = [[Transcription (genetics)|Transcription inhibitor]]s
| group2 = [[Transcription (genetics)|Transcription inhibitor]]s
| list2  = [[Tat_(HIV)#Clinical_significance|Tat antagonist]]s
| list2  =
* [[Tat (HIV)#Clinical significance|Tat antagonist]]s


| group3 = [[Antiviral_drug#Translation_.2F_ribozymes|Translation inhibitor]]s
| group3 = [[Antiviral drug#Translation .2F ribozymes|Translation inhibitor]]s
| list3  = [[Trichosanthin]]
| list3  =
* [[Trichosanthin]]


| group4 = Other
| group4 = Other
| list4  = [[Abzyme]]{{·}} [[Calanolide A]]{{·}} [[Ceragenin]]{{·}} [[Cyanovirin-N]]{{·}} [[Diarylpyrimidines]]{{·}} [[Epigallocatechin gallate|Epigallocatechin gallate (EGCG)]]{{·}} [[Foscarnet]]{{·}} [[Griffithsin]]{{·}} [[Hydroxycarbamide]]{{·}} [[Miltefosine]]{{·}} [[Portmanteau inhibitor]]s{{·}} [[Seliciclib]]<sup>†</sup>{{·}} [[Synergistic enhancer (antiretroviral)|Synergistic enhancer]]s{{·}} [[Tre recombinase]]{{·}} [[Zinc finger protein transcription factor]]{{·}} [[Error catastrophe#KP-1461|KP-1461]]<sup>†</sup>
| list4  =
 
* [[Abzyme]]
* [[Calanolide A]]
* [[Ceragenin]]
* [[Cyanovirin-N]]
* [[Diarylpyrimidines]]
* [[Epigallocatechin gallate|Epigallocatechin gallate (EGCG)]]
* [[Foscarnet]]
* [[Griffithsin]]
* [[Hydroxycarbamide]]
* [[Miltefosine]]
* [[Portmanteau inhibitor]]s
* [[Seliciclib]]<sup>†</sup>
* [[Synergistic enhancer (antiretroviral)|Synergistic enhancer]]s
* [[Tre recombinase]]
* [[Zinc finger protein transcription factor]]
* [[Error catastrophe#KP-1461|KP-1461]]<sup>†</sup>
* [[Cobicistat]]<sup>†</sup>
| group5 = Failed agents
| group5 = Failed agents
| list5  = [[Dexelvucitabine]]{{·}} [[Capravirine]]{{·}} [[Emivirine]]{{·}} [[Lodenosine]]{{·}} [[Atevirdine]]{{·}} [[Brecanavir]]{{·}} [[Aplaviroc]]
| list5  =
* [[Dexelvucitabine]]
* [[Capravirine]]
* [[Emivirine]]
* [[Lodenosine]]
* [[Atevirdine]]
* [[Brecanavir]]
* [[Aplaviroc]]
}}  
}}  


|belowstyle = background: transparent; padding: 0px;
|below = {{PharmNavFootnote}} °[[United States Department of Health and Human Services|DHHS]] preferred [[first-line treatment|first-line agent]]. <sup>◊</sup>Formerly or rarely used agent.<BR>{{Virus navs}}
|below = {{PharmNavFootnote}} °[[United States Department of Health and Human Services|DHHS]] preferred [[first-line treatment|first-line agent]]. <sup>◊</sup>Formerly or rarely used agent.<BR>{{Virus navs}}
}}<noinclude>
}}<noinclude>
[[تصنيف:جداول تصفح الأدوية|{{PAGENAME}}]]
[[تصنيف:جداول تصفح الأدوية]]
[[Category:Antiretroviral drugs|{{PAGENAME}}]]  
</noinclude>
</noinclude>

المراجعة الحالية بتاريخ 14:00، 9 أغسطس 2013

مجلوبة من «http://www.arabsciencepedia.org/w/index.php?title=قالب:مضادات_الفيروسات_القهقرية_المستخدمة_ضد_فيروس_الإيدز&oldid=28049»