أوكسيتورون

أوكسيتورون
Systematic (IUPAC) name
	(3Z)-3-[1]benzofuro[3,2-c][1]benzoxepin-6(12H)-ylidene-N,N-dimethylpropan-1-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	26020-55-3
ATC code	N02CX06
PubChem	CID 6436540
ChemSpider	21173074
UNII	T3XOS33TIQ
KEGG	D08312
Chemical data
Formula	C21H21NO2
Mol. mass	319.40 g/mol
	SMILES CN(C)CCC=C1C2=CC=CC=C2OCC3=C1OC4=CC=CC=C34;
	InChI InChI=1S/C21H21NO2/c1-22(2)13-7-10-17-15-8-3-5-11-19(15)23-14-18-16-9-4-6-12-20(16)24-21(17)18/h3-6,8-12H,7,13-14H2,1-2H3; Key:VZVRZTZPHOHSCK-UHFFFAOYSA-N;
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, as oxetorone fumarate (USAN) (brand names Nocertone, Oxedix), is a serotonin antagonist, antihistamine, and alpha blocker used as an antimigraine drug.[1][2][3][4]

Association with hyperprolactinemia has been described.[5]

على شكل أوكسيترون فومارات (USAN) (الأسماء التجارية نوسرتون، أوكسيديكس)، هو مضاد للسيروتونين، مضاد للهيستامين، وحاجب لألفا يستخدم كعقار مضاد للشقيقة.^[1]^[2]^[3]^[4]

وقد لوحظ ارتباطه فرط برولاكتين الدم.^[5]

مصادر

↑ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1493–. ISBN 978-0-412-46630-4.
↑ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 2935–. ISBN 978-0-8155-1856-3.
↑ C.J. van Boxtel; B. Santoso; I.R. Edwards (6 August 2008). Drug Benefits and Risks: International Textbook of Clinical Pharmacology - Revised 2nd Edition. IOS Press. pp. 699–. ISBN 978-1-60750-345-3.
↑ Massiou H (2000). "[Prophylactic treatments of migraine]". Rev. Neurol. (Paris) (in French). 156 Suppl 4: 4S79–86. PMID 11139754.
↑ Pradalier A (December 1996). "Hyperprolactinaemia and depression induced by oxetorone". Cephalalgia. 16 (8): 560–1. PMID 8980859. doi:10.1046/j.1468-2982.1996.1608560.x.

مصادر

[GanellinTriggle1996-1] C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1493–. ISBN 978-0-412-46630-4.

[Publishing2013-2] William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 2935–. ISBN 978-0-8155-1856-3.

[BoxtelSantoso2008-3] C.J. van Boxtel; B. Santoso; I.R. Edwards (6 August 2008). Drug Benefits and Risks: International Textbook of Clinical Pharmacology - Revised 2nd Edition. IOS Press. pp. 699–. ISBN 978-1-60750-345-3.

[pmid11139754-4] Massiou H (2000). "[Prophylactic treatments of migraine]". Rev. Neurol. (Paris) (in French). 156 Suppl 4: 4S79–86. PMID 11139754.

[pmid8980859-5] Pradalier A (December 1996). "Hyperprolactinaemia and depression induced by oxetorone". Cephalalgia. 16 (8): 560–1. PMID 8980859. doi:10.1046/j.1468-2982.1996.1608560.x.

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أوكسيتورون

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