الفرق بين المراجعتين لصفحة: «قالب:هيستامينات»
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{{Navbox | {{Navbox | ||
| name = | | name = الهيستامينات | ||
| title = الهيستامينات<br /> | | title = الهيستامينات<br /> | ||
(الناهضات والمثبطات)<br /> | (الناهضات والمثبطات)<br /> | ||
سطر 16: | سطر 16: | ||
| group1 = [[Histamine H1 receptor|H<sub>1</sub>]] | | group1 = [[Histamine H1 receptor|H<sub>1</sub>]] | ||
| list1 = | | list1 = | ||
'''Agonists''': [[2-Pyridylethylamine]] * [[Betahistine]] * [[Histamine]] * [[Histamine trifluoromethyl toluidide|HTMT]] * [[UR-AK49]]<br/>'''Antagonists''': ''1st generation'': [[4-Methyldiphenhydramine]] * [[Alimemazine]] * [[Antazoline]] * [[Azatadine]] * [[Bamipine]]*[[Benzatropine|Benzatropine/Benztropine]] * [[Bepotastine]] * [[Bromazine]] * [[Brompheniramine]] * [[Buclizine]] * [[Captodiame]] * [[Carbinoxamine]] * [[Chlorcyclizine]] * [[Chloropyramine]] * [[Chlorothen]] * [[Chlorphenamine]] * [[Chlorphenoxamine]] * [[Cinnarizine]]* [[Clemastine]] * [[Clobenzepam]] * [[Clocinizine]] * [[Cyclizine]] * [[Cyproheptadine]] * [[Dacemazine]] * [[Deptropine]]* [[Dexbrompheniramine]] * [[Dexchlorpheniramine]] * [[Dimenhydrinate]] * [[Dimetindene]] * [[Diphenhydramine]] * [[Diphenylpyraline]] * [[Doxylamine]] * [[Embramine]] * [[Etodroxizine]] * [[Etybenzatropine|Etybenzatropine/Ethylbenztropine]] * [[Etymemazine]] * [[Flunarizine]] * [[Histapyrrodine]] * [[Homochlorcyclizine]] * [[Hydroxyethylpromethazine]] * [[Hydroxyzine]] * [[Isopromethazine]] * [[Isothipendyl]] * [[Meclozine]] * [[Mepyramine|Mepyramine/Pyrilamine]] * [[Mequitazine]] * [[Methafurylene]] * [[Methapyrilene]] * [[Methdilazine]] * [[Moxastine]] * [[Niaprazine]] * [[Orphenadrine]] * [[Oxatomide]] * [[Oxomemazine]] * [[Phenindamine]] * [[Pheniramine]] * [[Phenyltoloxamine]] * [[Pimethixene]] * [[Piperoxan]] * [[Pipoxizine]] * [[Promethazine]] * [[Propiomazine]] * [[Pyrrobutamine]] * [[Talastine]] * [[Thenalidine]] * [[Thenyldiamine]] * [[Thiazinamium]] * [[Thonzylamine]] * [[Tolpropamine]] * [[Tripelennamine]] * [[Triprolidine]] | |||
* [[Betahistine]] | |||
* [[Histamine]] | |||
* [[Histamine trifluoromethyl toluidide|HTMT]] | |||
* [[UR-AK49]]<br/>'''Antagonists''': ''1st generation'': [[4-Methyldiphenhydramine]] | |||
* [[Alimemazine]] | |||
* [[Antazoline]] | |||
* [[Azatadine]] | |||
* [[Bamipine]] | |||
* [[Benzatropine|Benzatropine/Benztropine]] | |||
* [[Bepotastine]] | |||
* [[Bromazine]] | |||
* [[Brompheniramine]] | |||
* [[Buclizine]] | |||
* [[Captodiame]] | |||
* [[Carbinoxamine]] | |||
* [[Chlorcyclizine]] | |||
* [[Chloropyramine]] | |||
* [[Chlorothen]] | |||
* [[Chlorphenamine]] | |||
* [[Chlorphenoxamine]] | |||
* [[Cinnarizine]] | |||
* [[Clemastine]] | |||
* [[Clobenzepam]] | |||
* [[Clocinizine]] | |||
* [[Cyclizine]] | |||
* [[Cyproheptadine]] | |||
* [[Dacemazine]] | |||
* [[Deptropine]] | |||
* [[Dexbrompheniramine]] | |||
* [[Dexchlorpheniramine]] | |||
* [[Dimenhydrinate]] | |||
* [[Dimetindene]] | |||
* [[Diphenhydramine]] | |||
* [[Diphenylpyraline]] | |||
* [[Doxylamine]] | |||
* [[Embramine]] | |||
* [[Etodroxizine]] | |||
* [[Etybenzatropine|Etybenzatropine/Ethylbenztropine]] | |||
* [[Etymemazine]] | |||
* [[Flunarizine]] | |||
* [[Histapyrrodine]] | |||
* [[Homochlorcyclizine]] | |||
* [[Hydroxyethylpromethazine]] | |||
* [[Hydroxyzine]] | |||
* [[Isopromethazine]] | |||
* [[Isothipendyl]] | |||
* [[Meclozine]] | |||
* [[Mepyramine|Mepyramine/Pyrilamine]] | |||
* [[Mequitazine]] | |||
* [[Methafurylene]] | |||
* [[Methapyrilene]] | |||
* [[Methdilazine]] | |||
* [[Moxastine]] | |||
* [[Niaprazine]] | |||
* [[Orphenadrine]] | |||
* [[Oxatomide]] | |||
* [[Oxomemazine]] | |||
* [[Phenindamine]] | |||
* [[Pheniramine]] | |||
* [[Phenyltoloxamine]] | |||
* [[Pimethixene]] | |||
* [[Piperoxan]] | |||
* [[Pipoxizine]] | |||
* [[Promethazine]] | |||
* [[Propiomazine]] | |||
* [[Pyrrobutamine]] | |||
* [[Talastine]] | |||
* [[Thenalidine]] | |||
* [[Thenyldiamine]] | |||
* [[Thiazinamium]] | |||
* [[Thonzylamine]] | |||
* [[Tolpropamine]] | |||
* [[Tripelennamine]] | |||
* [[Triprolidine]] | |||
''2nd generation'': [[Acrivastine]] * [[Alinastine]] * [[Astemizole]] * [[Azelastine]] * [[Bamirastine]] * [[Barmastine]] * [[Bepiastine]]* [[Bepotastine]] * [[Bilastine]] * [[Cabastinen]] * [[Carebastine]] * [[Cetirizine]] * [[Clemastine]] * [[Clemizole]] * [[Clobenztropine]] * [[Dorastine]] * [[Ebastine]] * [[Emedastine]] * [[Epinastine]] * [[Flezelastine]] * [[Ketotifen]] * [[Latrepirdine]]* [[Levocabastine]] * [[Linetastine]] * [[Loratadine]] * [[Mapinastine]] * [[Mebhydrolin]] * [[Mizolastine]] * [[Moxastine]] * [[Noberastine]] * [[Octastine]] * [[Olopatadine]] * [[Perastine]] * [[Piclopastine]] * [[Rocastine]] * [[Rupatadine]] * [[Setastine]] * [[Talastine]] * [[Temelastine]] * [[Terfenadine]] * [[Zepastine]] | |||
* [[Alinastine]] | |||
* [[Astemizole]] | |||
* [[Azelastine]] | |||
* [[Bamirastine]] | |||
* [[Barmastine]] | |||
* [[Bepiastine]] | |||
* [[Bepotastine]] | |||
* [[Bilastine]] | |||
* [[Cabastinen]] | |||
* [[Carebastine]] | |||
* [[Cetirizine]] | |||
* [[Clemastine]] | |||
* [[Clemizole]] | |||
* [[Clobenztropine]] | |||
* [[Dorastine]] | |||
* [[Ebastine]] | |||
* [[Emedastine]] | |||
* [[Epinastine]] | |||
* [[Flezelastine]] | |||
* [[Ketotifen]] | |||
* [[Latrepirdine]] | |||
* [[Levocabastine]] | |||
* [[Linetastine]] | |||
* [[Loratadine]] | |||
* [[Mapinastine]] | |||
* [[Mebhydrolin]] | |||
* [[Mizolastine]] | |||
* [[Moxastine]] | |||
* [[Noberastine]] | |||
* [[Octastine]] | |||
* [[Olopatadine]] | |||
* [[Perastine]] | |||
* [[Piclopastine]] | |||
* [[Rocastine]] | |||
* [[Rupatadine]] | |||
* [[Setastine]] | |||
* [[Talastine]] | |||
* [[Temelastine]] | |||
* [[Terfenadine]] | |||
* [[Zepastine]] | |||
''3rd generation'': [[Desloratadine]] * [[Fexofenadine]] * [[Levocetirizine]] | |||
* [[Fexofenadine]] | |||
* [[Levocetirizine]] | |||
''Ungrouped'': [[Belarizine]] * [[Efletirizine]] * [[Elbanizine]] * [[Flotrenizine]] * [[Medrylamine]] * [[Napactadine]] * [[Pibaxizine]]* [[Tagorizine]] * [[Trelnarizine]] * [[Trenizine]] * [[Vapitadine]] | |||
* [[Efletirizine]] | |||
* [[Elbanizine]] | |||
* [[Flotrenizine]] | |||
* [[Medrylamine]] | |||
* [[Napactadine]] | |||
* [[Pibaxizine]] | |||
* [[Tagorizine]] | |||
* [[Trelnarizine]] | |||
* [[Trenizine]] | |||
* [[Vapitadine]] | |||
''Miscellaneous'': [[Tricyclic antidepressant]]s ([[amitriptyline]], * [[doxepin]], * [[trimipramine]], etc) * [[Tetracyclic antidepressant]]s ([[mianserin]], * [[mirtazapine]], etc) * [[Typical antipsychotic]]s ([[chlorpromazine]], * [[thioridazine]], etc) * [[Atypical antipsychotic]]s ([[clozapine]], * [[olanzapine]], * [[quetiapine]], etc) | |||
* [[doxepin]], | |||
* [[trimipramine]], etc) | |||
* [[Tetracyclic antidepressant]]s ([[mianserin]], | |||
* [[mirtazapine]], etc) | |||
* [[Typical antipsychotic]]s ([[chlorpromazine]], | |||
* [[thioridazine]], etc) | |||
* [[Atypical antipsychotic]]s ([[clozapine]], | |||
* [[olanzapine]], | |||
* [[quetiapine]], etc) | |||
| group2 = [[Histamine H2 receptor|H<sub>2</sub>]] | | group2 = [[Histamine H2 receptor|H<sub>2</sub>]] | ||
| list2 = | | list2 = | ||
'''Agonists''': [[Amthamine]] * [[Betazole]] * [[Dimaprit]] * [[Histamine]] * [[Histamine trifluoromethyl toluidide|HTMT]] * [[Impromidine]] * [[UR-AK49]]<br/>'''Antagonists''': [[Bisfentidine]] [[Burimamide]] * [[Cimetidine]] * [[Dalcotidine]] * [[Donetidine]] * [[Ebrotidine]] * [[Etintidine]] * [[Famotidine]] * [[Lafutidine]] * [[Lamtidine]] * [[Lavoltidine|Lavoltidine/Loxtidine]] * [[Lupitidine]] * [[Metiamide]]* [[Mifentidine]] * [[Niperotidine]] * [[Nizatidine]] * [[Osutidine]] * [[Oxmetidine]] * [[Pibutidine]] * [[Quisultazine|Quisultazine/Quisultidine]] * [[Ramixotidine]] * [[Ranitidine]] * [[Roxatidine]] * [[Sufotidine]] * [[Tiotidine]] * [[Tuvatidine]] * [[Venritidine]] * [[Xaltidine]] | |||
* [[Betazole]] | |||
* [[Dimaprit]] | |||
* [[Histamine]] | |||
* [[Histamine trifluoromethyl toluidide|HTMT]] | |||
* [[Impromidine]] | |||
* [[UR-AK49]]<br/>'''Antagonists''': [[Bisfentidine]] | |||
* [[Cimetidine]] | |||
* [[Dalcotidine]] | |||
* [[Donetidine]] | |||
* [[Ebrotidine]] | |||
* [[Etintidine]] | |||
* [[Famotidine]] | |||
* [[Lafutidine]] | |||
* [[Lamtidine]] | |||
* [[Lavoltidine|Lavoltidine/Loxtidine]] | |||
* [[Lupitidine]] | |||
* [[Metiamide]] | |||
* [[Mifentidine]] | |||
* [[Niperotidine]] | |||
* [[Nizatidine]] | |||
* [[Osutidine]] | |||
* [[Oxmetidine]] | |||
* [[Pibutidine]] | |||
* [[Quisultazine|Quisultazine/Quisultidine]] | |||
* [[Ramixotidine]] | |||
* [[Ranitidine]] | |||
* [[Roxatidine]] | |||
* [[Sufotidine]] | |||
* [[Tiotidine]] | |||
* [[Tuvatidine]] | |||
* [[Venritidine]] | |||
* [[Xaltidine]] | |||
| group3 = [[Histamine H3 receptor|H<sub>3</sub>]] | | group3 = [[Histamine H3 receptor|H<sub>3</sub>]] | ||
| list3 = | | list3 = | ||
'''Agonists''': [[alpha-Methylhistamine|ل-Methylhistamine]] * [[Cipralisant]] * [[Histamine]] * [[Imetit]] * [[Immepip]] * [[Immethridine]] * [[Methimepip]] * [[Proxyfan]]<br/>'''Antagonists''': [[A-349,821]] * [[A-423,579]] * [[ABT-239]] * [[Betahistine]] * [[Burimamide]] * [[Ciproxifan]] * [[Clobenpropit]] * [[Conessine]] * [[GSK-189,254]] * [[Impentamine]] * [[Iodophenpropit]] * [[JNJ-5207852|JNJ-5,207,852]] * [[MK-0249]] * [[NNC 38-1049|NNC-38-1,049]] * [[PF-03654746]] * [[Pitolisant]] * [[SCH-79687|SCH-79,687]] * [[Thioperamide]] * [[VUF-5681|VUF-5,681]] | |||
* [[Cipralisant]] | |||
* [[Histamine]] | |||
* [[Imetit]] | |||
* [[Immepip]] | |||
* [[Immethridine]] | |||
* [[Methimepip]] | |||
* [[Proxyfan]]<br/>'''Antagonists''': [[A-349,821]] | |||
* [[A-423,579]] | |||
* [[ABT-239]] | |||
* [[Betahistine]] | |||
* [[Burimamide]] | |||
* [[Ciproxifan]] | |||
* [[Clobenpropit]] | |||
* [[Conessine]] | |||
* [[GSK-189,254]] | |||
* [[Impentamine]] | |||
* [[Iodophenpropit]] | |||
* [[JNJ-5207852|JNJ-5,207,852]] | |||
* [[MK-0249]] | |||
* [[NNC 38-1049|NNC-38-1,049]] | |||
* [[PF-03654746]] | |||
* [[Pitolisant]] | |||
* [[SCH-79687|SCH-79,687]] | |||
* [[Thioperamide]] | |||
* [[VUF-5681|VUF-5,681]] | |||
| group4 = [[Histamine H4 receptor|H<sub>4</sub>]] | | group4 = [[Histamine H4 receptor|H<sub>4</sub>]] | ||
| list4 = | | list4 = | ||
'''Agonists''': [[4-Methylhistamine]] * [[Histamine]] * [[VUF-8430|VUF-8,430]]<br/>'''Antagonists''': [[JNJ-7777120|JNJ-7,777,120]] [[Thioperamide]] * [[VUF-6002|VUF-6,002]] | |||
* [[Histamine]] | |||
* [[VUF-8430|VUF-8,430]]<br/>'''Antagonists''': [[JNJ-7777120|JNJ-7,777,120]] | |||
* [[VUF-6002|VUF-6,002]] | |||
}} | }} | ||
سطر 244: | سطر 47: | ||
| group1 = [[Vesicular monoamine transporter|VMAT]] | | group1 = [[Vesicular monoamine transporter|VMAT]] | ||
| list1 = | | list1 = | ||
'''Inhibitors:''' [[Ibogaine]] * [[Reserpine]] * [[Tetrabenazine]] | |||
* [[Reserpine]] | |||
* [[Tetrabenazine]] | |||
}} | }} | ||
سطر 257: | سطر 58: | ||
| group1 = [[Histidine decarboxylase|HDC]] | | group1 = [[Histidine decarboxylase|HDC]] | ||
| list1 = | | list1 = | ||
'''Inhibitors:''' [[(+)-Catechin|Catechin]] * [[Meciadanol]] * [[Naringenin]] * [[Tritoqualine]] | |||
* [[Meciadanol]] | |||
* [[Naringenin]] | |||
* [[Tritoqualine]] | |||
| group2 = [[Histamine N-methyltransferase|HNMT]] | | group2 = [[Histamine N-methyltransferase|HNMT]] | ||
| list2 = | | list2 = | ||
'''Inhibitors:''' [[Amodiaquine]] * [[Diphenhydramine]] * [[Harmaline]] * [[Metoprine]] * [[Quinacrine]] * [[SKF-91,488]] * [[Tacrine]] | |||
* [[Diphenhydramine]] | |||
* [[Harmaline]] | |||
* [[Metoprine]] | |||
* [[Quinacrine]] | |||
* [[SKF-91,488]] | |||
* [[Tacrine]] | |||
| group2 = [[Diamine oxidase|DAO]] | | group2 = [[Diamine oxidase|DAO]] | ||
| list2 = | | list2 = | ||
'''Inhibitors:''' [[Aminoguanidine]] | |||
}} | }} | ||
سطر 284: | سطر 76: | ||
| group1 = Endogenous | | group1 = Endogenous | ||
| list1 = | | list1 = | ||
[[Histamine]]; ''Precursors:'' [[L-Histidine|<small>L</small>-Histidine]]; ''Cofactors:'' [[Vitamin B6]] | |||
}} | }} |