عرض مصدر سيكريمين

{{Drugbox
| IUPAC_name = 1-Cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
| image = Cycrimine.svg
| width =
| alt = 
| image2 = 
| width2 = 
| drug_name = 
<!--Clinical data-->
| tradename = 
| licence_EU = <!-- EMA requires brand name -->
| licence_US = Cycrimine
| DailyMedID = <!-- preference to licence_US -->
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B            / C / D / X -->
| pregnancy_category = 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
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<!--Pharmacokinetic data-->
| bioavailability = 
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<!--Identifiers-->
| CAS_number = 77-39-4
| CAS_supplemental = 
| ATCvet = 
| ATC_prefix = none
| ATC_suffix = 
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| IUPHAR_ligand = 
| DrugBank = DB00942
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 59692
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 543567RFQQ
| ChEMBL = 1201227
| synonyms = 
| PubChem = 2911
| ChemSpiderID = 2808
| StdInChI = 1S/C19H29NO/c21-19(18-11-5-6-12-18,17-9-3-1-4-10-17)13-16-20-14-7-2-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
| StdInChIKey = SWRUZBWLEWHWRI-UHFFFAOYSA-N
<!--Chemical data-->
| chemical_formula =
| C=19 | H=29 | N=1 | O=1
| molecular_weight = 287.4 g/mol
| SMILES = OC(CCN1CCCCC1)(C2CCCC2)c3ccccc3
| density = 
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}}

'''سيكريمين Cycrimine''' (الاسم التجاري Pagitane) هو دواء مركزي مضاد لل[[كولين]] مصمم لتقليل مستويات [[أستيل كولين]] لعلاج [[مرض باركنسون]].
 آلية عمله هي الارتباط بمستقبلات [[أستيل كولين]] ال[[مسكارين]]ية M1.<ref>''Psychotropic Drugs and Related Compounds'', 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, page 218</ref>

==الاصطناع==
==Synthesis==
[[File:Cycrimine synthesis.png|thumb|center|500px|Cycrimine synthesis:<ref>{{cite journal|last1=Denton|first1=J. J.|last2=Schedl|first2=H. P.|last3=Lawson|first3=Virginia A.|last4=Neier|first4=W. B.|title=Antispasmodics. VII.<sup>1</sup> Additional Morpholinyl and Piperidyl Tertiary Alcohols|journal=Journal of the American Chemical Society|volume=72|issue=8|year=1950|pages=3795–3796|doi=10.1021/ja01164a127}}</ref>]]

==المصدر==
{{مراجع}}

{{أدوية معالجة داء باركنسون}}
[[تصنيف:أدوية]]
[[تصنيف:موسوعة الأدوية]]
[[تصنيف:أدوية معالجة داء باركنسون]]