روباتادين Rupatadine يعدّ مضاد هيستامين جيل ثاني, غير مركن, ذو فعالية مناهضة للعامل المفعّل للصفيحات (PAF) حيث يستخدم لمعالجة التهاب الأنف التحسسي والشرى المزمن مجهولة السبب. يعطى على شكل فومارات لكن يعبر عن الجرعة على أساس الشكل الأساسي، يكافئ 12,8ملغ Rupatadine fumarate حوالي 10ملغ Rupatadine. وتكون الجرعة الفموية المعتادة مايعادل 10 ملغ مرة يومياً من Rupatadine.
آلية العمل
مناهض مطول التأثير لمستقبلات H1.
الآثار الجانبية
المصدر
http://en.wikipedia.org/wiki/Rupatadine
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حسب المستقبل
Receptor | | Agonists: 2-Pyridylethylamine * Betahistine * Histamine * HTMT * UR-AK49Antagonists: 1st generation: 4-Methyldiphenhydramine * Alimemazine * Antazoline * Azatadine * Bamipine* Benzatropine/Benztropine * Bepotastine * Bromazine * Brompheniramine * Buclizine * Captodiame * Carbinoxamine * Chlorcyclizine * Chloropyramine * Chlorothen * Chlorphenamine * Chlorphenoxamine * Cinnarizine* Clemastine * Clobenzepam * Clocinizine * Cyclizine * Cyproheptadine * Dacemazine * Deptropine* Dexbrompheniramine * Dexchlorpheniramine * Dimenhydrinate * Dimetindene * Diphenhydramine * Diphenylpyraline * Doxylamine * Embramine * Etodroxizine * Etybenzatropine/Ethylbenztropine * Etymemazine * Flunarizine * Histapyrrodine * Homochlorcyclizine * Hydroxyethylpromethazine * Hydroxyzine * Isopromethazine * Isothipendyl * Meclozine * Mepyramine/Pyrilamine * Mequitazine * Methafurylene * Methapyrilene * Methdilazine * Moxastine * Niaprazine * Orphenadrine * Oxatomide * Oxomemazine * Phenindamine * Pheniramine * Phenyltoloxamine * Pimethixene * Piperoxan * Pipoxizine * Promethazine * Propiomazine * Pyrrobutamine * Talastine * Thenalidine * Thenyldiamine * Thiazinamium * Thonzylamine * Tolpropamine * Tripelennamine * Triprolidine
2nd generation: Acrivastine * Alinastine * Astemizole * Azelastine * Bamirastine * Barmastine * Bepiastine* Bepotastine * Bilastine * Cabastinen * Carebastine * Cetirizine * Clemastine * Clemizole * Clobenztropine * Dorastine * Ebastine * Emedastine * Epinastine * Flezelastine * Ketotifen * Latrepirdine* Levocabastine * Linetastine * Loratadine * Mapinastine * Mebhydrolin * Mizolastine * Moxastine * Noberastine * Octastine * Olopatadine * Perastine * Piclopastine * Rocastine * Rupatadine * Setastine * Talastine * Temelastine * Terfenadine * Zepastine
3rd generation: Desloratadine * Fexofenadine * Levocetirizine
Ungrouped: Belarizine * Efletirizine * Elbanizine * Flotrenizine * Medrylamine * Napactadine * Pibaxizine* Tagorizine * Trelnarizine * Trenizine * Vapitadine
Miscellaneous: Tricyclic antidepressants ( amitriptyline, * doxepin, * trimipramine, etc) * Tetracyclic antidepressants ( mianserin, * mirtazapine, etc) * Typical antipsychotics ( chlorpromazine, * thioridazine, etc) * Atypical antipsychotics ( clozapine, * olanzapine, * quetiapine, etc) |
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حسب الناقل العصبي
Transporter | |
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حسب الإنزيم
Enzyme | |
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