إيدوكسيدين

إيدوكسيدين
Systematic (IUPAC) name
	5-ethyl-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	15176-29-1
ATC code	D06BB09
PubChem	CID 66377
ChemSpider	59752
UNII	15ZQM81Y3R
ChEMBL	CHEMBL318153
Chemical data
Formula	C11H16N2O5
Mol. mass	256.25514
	SMILES O=C/1NC(=O)N(\C=C\1CC)[C@@H]2O[C@@H]([C@@H](O)C2)CO;
	InChI InChI=1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1 ; Key:XACKNLSZYYIACO-DJLDLDEBSA-N ;
(what is this?) (verify);

هو دواء مضاد للفيروسات. وهو مناظر للثيميدين، النوكليوزيد. وقد أظهر فعالية ضد فيروس الهربس البسيط.

الاصطناع

Edoxudine synthesis:^[1] Synthesis via organopalladium intermediates:^[2]^[3]

↑ K. K. Gauri, GB 1170565; eidem, قالب:US patent (1968, 1971 both to Robugen).
↑ Bergstrom, Donald E.; Ruth, Jerry L. (1976). "Synthesis of C-5 substituted pyrimidine nucleosides via organopalladium intermediates". Journal of the American Chemical Society. 98 (6): 1587–9. PMID 1249369. doi:10.1021/ja00422a056.
↑ Bergstrom, Donald E.; Ogawa, Mark K. (1978). "C-5 substituted pyrimidine nucleosides. 2. Synthesis via olefin coupling to organopalladium intermediates derived from uridine and 2'-deoxyuridine". Journal of the American Chemical Society. 100 (26): 8106–8112. ISSN 0002-7863. doi:10.1021/ja00494a014.